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    The most important seo factor is KEYWORDS. Every website has specific keywords. What are your keywords? Keywords are the words that they use to lead visitors to your site. Keywords would generally include your company name, brand name, and any other words sp
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ecific to your company or product. Keywords should also reflect the mind-set of your customers, their needs and opinions, and how they would search for the products and services that you offer.

    1. Keywords use in URL - It certainly doesn't hurt, and provide
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    s bolded listings on many search results which assists clickthrough rates. First word have weight, second has less weight, the third and etc. This only influences rankings where you have many sites linking to that page using the URL as the anchor text. Don’t
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    overdo it.

    2. Keyword use in Domain name – It’s recommending to have at least one or two keywords in your domain name. Also try to use keywords in sub-domains. Using a keyword in the domain name is only helpful if you separate the words with hyphens. Big sp
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    eculation is that too many hyphens can harm the trust issue with the domain, so more than one or two hyphens is not recommended. A good brand name is always better than a keyword-filled domain.

    3. Keywords – Header - Placing the targeted search term or phra
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    e in the title, description and keyword tags of the web page's HTML header

    * Keyword use in Title tag - the title tag must be close to beginning. Not more than 10 - 60 characters, no special characters. Separate with coma. This title tag has consistently be
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    en the most important on-page SEO factor for the past few years.

    * Keyword use in Description tag - Shows theme and people use to read him. Descriptions are important. Need to be unique for each page and contain target keywords to encourage search engines t
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    o pull snippets from it. Estimate than 200 charcaters.

    * Keyword use in Keyword metatag - estimate than 10 words. Every word in this tag MUST appear somewhere in the body text. If not, it can be penalized for irrelevance.No single word should appear more th
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    n twice.If not, it may be considered spam. Google purportedly no longer uses this tag, but others do.

    4. Keywords - Body - Using the targeted search term in the visible, HTML text of the page. It is important to use the keyword phrase throughout the page wh
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ere it makes sense. As engines get more sophisticated, it's not just the targeted keyword phrase that counts, but the mix of all the words on the page that help to determine what the page is about.

    * Keyword density in body text – estimate 5% - 20% (all key
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    ords/ total words).

    * Individual keyword density – estimate 1% - 6% - (each keyword/ total words)

    * Keyword use in H1, H2 and H3 - Not as important as it once was as a ranking factor, but still necessary on a well optimized page and very useful for organiz
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    ing page content. May hurt your rankings if it is too well aligned with the page title and anchor text. If templating issues cause too much duplication in a large section of a website it may also lead to reduced crawling.

    * Keyword use in bold or strong tag
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    s - Bolds are for markup, strong is for emphasis. Strong is treated the same as bold, italic is treated the same as emphasis. Mark keywords in BOLD, italic, strong. Bold tags are great for catching readers that scan, and getting them to spend more time on a
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    age.

    * Keyword proximity (for 2+ keywords) - Directly adjacent is best. For targeting of two word searches keep keywords close to each other.

    * Keyword phrase order - The word order in the page must match word order in the query. Try to anticipate query, a
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    nd match word order.

    * Keyword prominence – The keyword must be early in the the tag. Can be important at top of page, in bold, in large font.

    5. Keywords - Other

    * Keyword in alt tags and image titles - When an image is used in place of anchor text, the
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    alt acts as anchor text. Alt attributes for linked images do have some importance when it comes to SEO. Alt attributes on regular images are important for usability. If you use the images for links, the alt tag is as important as the anchor text. Also, image
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    search delivers some traffic, so tag them anyway.

    * Keyword in links to site pages (anchor text) - Links out anchor text use keyword?

    * Age of Documents - Older pages may be perceived as more authoritative while newer pages may be more temporally relevant.
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products


    * Amount of Indexable page content - Refers to the literal quantity of visible HTML text on a page. This depends on how well the content is structured in relation to other relevant pages. Also, too much content on the page seems to still equal less stellar
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    results. The old rule was 200 words but we feel that as few as 75-100 can now be effective, if supported by other pages.

    * Document content - The document content is a huge factor in getting links, but is hard for an algorith to measure and weigh.

    * Organi
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    zation of document flow - Clear organization not only helps search engines understand how documents relate to each other, but also effectively distributes your link authority.

    * Frequency of updates to page - More updates the better. Keep that content fresh


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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